Chick Embryotoxicity Screening Test (CHEST I and II)
The chick embryo has been used for the study of experimental teratogenicity by various techniques (1, 2, 3, 4). This chapter describes a method developed by Jelinek (5,6) that combines a standardized technique (CHEST I) with other techniques (CHEST II); it allows the administration of small amounts of test compound and the measurement of a quantitative endpoint (CHEST I).
KeywordsDMSO Polyethylene Paraffin Carboxymethylcellulose Teratogenicity
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