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Bromoacetylated Synthetic Peptides

Starting Materials for Cyclic Peptides, Peptomers, and Peptide Conjugates
  • Frank A. Robey
Part of the Methods in Molecular Biology book series (MIMB, volume 35)

Abstract

Modern peptide synthesis techniques make it straightforward to synthesize linear peptides that are based on amino acid sequences of parent proteins. It is well known that the linear peptide itself often will not share the same activity as the peptide in its original biological environment provided by the native protein. In addition, the scientific reasons for making a peptide will often not be simply to mimic an activity of a protein—whatever it may be—with a small synthetic substitute, but the goal may be to enhance or decrease an activity found in a native protein. Therefore, it is important to be able to modify the conformations and configurations of a linear peptide by cyclizing, polymerizing, or conjugating the peptide.

Keywords

Cyclic Peptide Hydrogen Fluoride Free Thiol Linear Peptide Peptide Conjugate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Humana Press Inc. 1994

Authors and Affiliations

  • Frank A. Robey
    • 1
  1. 1.Peptide and Immunohistochemistry Unit, Laboratory of Cellular Development and OncologyNational Institute of Dental Research, National Institutes of HealthBethesdaUSA

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