Abstract
The Fragment Assembly System is a series of related programs that help you assemble overlapping fragment sequences as obtained at the lab bench. Specifically, the programs resemble a small databas system that helps you to achieve six major tasks:
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1.
Entering and storage of sequences in a project database (method 1).
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2.
Recognition of overlaps (method 2).
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3.
Manipulation of aligned fragments (this step and all following: method 3)
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4.
Generation and comparison of consensus sequences as determined from aligned fragments.
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5.
Display and archiving of aligned sequences.
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6.
Determination of the consensus sequence.
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References
Staden, R. (1980) A new computer method for the storage manipulation of DNA gel reading data. Nucl. Acids Res. 11, 3673–3694.
Devereux, J., Haeberli, P., and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucl. Acids Res. 12, 387–395.
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© 1994 Humana Press Inc., Totowa, NJ
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Dölz, R. (1994). GCG: Fragment Assembly Programs. In: Griffin, A.M., Griffin, H.G. (eds) Computer Analysis of Sequence Data. Methods in Molecular Biology, vol 24. Humana Press. https://doi.org/10.1385/0-89603-246-9:9
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DOI: https://doi.org/10.1385/0-89603-246-9:9
Publisher Name: Humana Press
Print ISBN: 978-0-89603-246-0
Online ISBN: 978-1-59259-511-2
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