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High-Mannose Chains of Mammalian Glycoproteins

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 14))

Abstract

High-mannose oligosaccharides are commonly associated with the glycoproteins of most living organisms, and a variety of techniques are available for determining the relative amounts of high-mannose and complex oligosaccharides (14). The high-mannose chains of mammalian glycoproteins are often comprised of a series of oligosaccharides having the composition Man5–8GlcNAc2 (Man5–8). Although the relative amounts of each class of high-mannose oligosaccharide (i.e., Man5, Man6, and so on) have been examined during processing of some glycoproteins, relatively little work on the high-mannose “profile” of mature glycoproteins has been carried out.

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© 1993 Humana Press Inc., Totowa, NJ

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Sherblom, A.P., Smagula, R.M. (1993). High-Mannose Chains of Mammalian Glycoproteins. In: Hounsell, E.F. (eds) Glycoprotein Analysis in Biomedicine. Methods in Molecular Biology, vol 14. Humana Press. https://doi.org/10.1385/0-89603-226-4:143

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  • DOI: https://doi.org/10.1385/0-89603-226-4:143

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-226-2

  • Online ISBN: 978-1-59259-501-3

  • eBook Packages: Springer Protocols

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