Methods for Drug Studies in Aggressive Behavior

  • Michael H. Sheard
Part of the Neuromethods book series (NM, volume 19)


Behavioral pharmacology is the detection, description, and explanation of drug effects on behavior. It can be divided into four subsections:
  1. 1.

    The neurochemical or physiological basis of behavior is investigated by using drugs with a known mechanism of action;

  2. 2.

    Behavior is used to measure the potency, spectrum of action, and structure-activity relationships of drugs;

  3. 3.

    Drugs can be used to produce models of pathological conditions; and

  4. 4.

    The mechanism of action of drugs can be investigated, such as their electrophysiological or neurochemical basis.


These four areas clearly require different methods, and aggressive behavior can be used in all of them.


Placebo Lithium Cage Epoxy Syringe 


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Copyright information

© The Humana Press Inc. 1991

Authors and Affiliations

  • Michael H. Sheard
    • 1
  1. 1.Department of PsychiatryYale University School of MedicineNew HavenConnecticut

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