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Carbohydrates and Energy Metabolism pp 155–193Cite as

The [14C]Deoxyglucose Method for Measurement of Local Cerebral Glucose Utilization

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Part of the book series: Neuromethods ((NM,volume 11))

Abstract

The brain is a complex, heterogeneous organ composed of many anatomical and functional components with markedly different levels of functional activity that vary independently with time and function. Other tissues are generally far more homogeneous, with most of their cells functioning similarly and synchronously in response to a common stimulus or regulatory influence. The central nervous system, however, consists of innumerable subunits, each integrated into its own set of functional pathways and networks, and subserving only one or a few of the many activities in which the nervous system participates. Understanding how the nervous system functions requires knowledge not only of the mechanisms of excitation and inhibition, but even more so of their precise localization in the nervous system and the relationships of neural subunits to specific functions.

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Author information

Authors and Affiliations

  1. U. S. Department of Health and Human Services, National Institute of Mental Health, Bethesda, MD

    Louis Sokoloff & Carolyn B. Smith

  2. Department of Pediatrics, Georgetown University School of Medicine, Washington, D. C.

    Charles Kennedy

Authors
  1. Louis Sokoloff
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  2. Charles Kennedy
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  3. Carolyn B. Smith
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Editor information

Editors and Affiliations

  1. University of Saskatchewan, Saskatoon, Canada

    Alan A. Boulton

  2. University of Alberta, Edmonton, Canada

    Glen B. Baker

  3. University of Montreal, Montreal, Canada

    Roger F. Butterworth

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© 1989 The Humana Press Inc

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Sokoloff, L., Kennedy, C., Smith, C.B. (1989). The [14C]Deoxyglucose Method for Measurement of Local Cerebral Glucose Utilization. In: Boulton, A.A., Baker, G.B., Butterworth, R.F. (eds) Carbohydrates and Energy Metabolism. Neuromethods, vol 11. Humana Press, Totowa, NJ. https://doi.org/10.1385/0-89603-143-8:155

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  • DOI: https://doi.org/10.1385/0-89603-143-8:155

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-0-89603-143-2

  • Online ISBN: 978-1-59259-616-4

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