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Peptides pp 299–347Cite as

Behavioral Tests

Their Interpretation and Significance in the Study of Peptide Action

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Part of the book series: Neuromethods ((NM,volume 6))

Abstract

Neuropeptides (i.e., peptides found in the nervous system) have received wide general acceptance as regulators of neuronal activity (e.g., Krieger and Liotta, 1979; Hokfelt, 1980). In many cases, neuropeptides were previously known as peptide hormones or had been first isolated from other tissues, frequently the gut. In other cases, hypothalamic peptides known to serve as releasing hormones (i.e., molecules released from the hypothalamus that could either stimulate or inhibit the release of hormones from the pituitary) were subsequently found to have an independent existence elsewhere in the central nervous system (CNS). In some cases, peptides were first discovered in extracts of brain tissue, and, m a very few cases so far, deduced from mRNA sequences found in only a relatively small population of neurons (Sutcliffe et al., 1983). In all cases, neuropeptides appear to have powerful activities as regulators of nervous system function.

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Author information

Authors and Affiliations

  1. Department of Neuroscience, University of Florida College of Medicine, Gainesville, Florida

    Adrian J. Dunn & Craig W. Berridge

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  1. Adrian J. Dunn
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  2. Craig W. Berridge
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Editor information

Editors and Affiliations

  1. University of Saskatchewan, Canada

    Alan A. Boulton

  2. University of Alberta, Canada

    Glen B. Baker

  3. University of Calgary, Canada

    Q. J. Pittman

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© 1987 The Humana Press Inc.

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Dunn, A.J., Berridge, C.W. (1987). Behavioral Tests. In: Boulton, A.A., Baker, G.B., Pittman, Q.J. (eds) Peptides. Neuromethods, vol 6. Humana Press. https://doi.org/10.1385/0-89603-105-5:299

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  • DOI: https://doi.org/10.1385/0-89603-105-5:299

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-105-0

  • Online ISBN: 978-1-59259-611-9

  • eBook Packages: Springer Protocols

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