Computer Analysis of 2-D Images

  • Patricia M. Palagi
  • Daniel Walther
  • Gérard Bouchet
  • Sonja Voordijk
  • Ron D. Appel
Part of the Springer Protocols Handbooks book series (SPH)


Indeed, the development of two-dimensional (2-D) electrophoresis technology has provided an important research tool for comparative proteomics. A number of other technologies for protein separation have also been investigated in the last few years, such as protein chips, liquid chromatography, and high-pressure liquid chromatography, to name just a few. However, 2-D gels are still considered the workhorse among research laboratories willing to accurately track changes in protein expression and to achieve differential proteomics.


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Copyright information

© Humana Press Inc., Totowa, NJ 2005

Authors and Affiliations

  • Patricia M. Palagi
    • 1
  • Daniel Walther
    • 2
  • Gérard Bouchet
    • 2
  • Sonja Voordijk
    • 3
  • Ron D. Appel
    • 4
  1. 1.Swiss Institute of BioinformaticsGeneva University HospitalGenevaSwitzerland
  2. 2.Swiss Institute of BioinformaticsGenevaSwitzerland
  3. 3.Geneva Bioinformatics S. A.GenevaSwitzerland
  4. 4.Swiss Institute of BioinformaticsUniversity and Geneva University HospitalGenevaSwitzerland

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