Amplification Refractory Mutation System and Molecular Diagnostics

  • Richard Kitching
  • Arun Seth
Part of the Springer Protocols Handbooks book series (SPH)


Allele-specific polymerase chain reaction (PCR) was first described in 1989, with variations arising over the next few years such as allele-specific oligonucleotide PCR, mutant-allele-specific amplification (MASA), PCR amplification of specific alleles (PASA), and the amplification refractory mutation system (ARMS) (1, 2, 3, 4, 5). For convenience, the term ARMS will be used here when referring to them collectively.


Human Papilloma Virus Fluorescence Resonance Energy Transfer Medullary Thyroid Carcinoma Amplification Refractory Mutation System Polymerase Chain Reaction Machine 
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Copyright information

© Humana Press Inc., Totowa, NJ 2005

Authors and Affiliations

  • Richard Kitching
    • 1
  • Arun Seth
    • 1
  1. 1.Department of Laboratory Medicine and Pathobiology, Sunnybrook and Women’s College Health Sciences CentreUniversity of TorontoTorontoCanada

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