Digital Recording of Patch-Clamp Data

  • Shigeru Morishima
  • Andrew F. James
Part of the Springer Protocols Handbooks book series (SPH)


Patch-clamp data, including channel currents and membrane voltage, are usually recorded to a computer via a process known as analog-to-digital conversion. This chapter gives essential information on how to avoid pitfalls and obtain error-free data with optimal resolution.


Sampling Frequency Cutoff Frequency Original Signal Current Signal Voltage Signal 
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Copyright information

© Springer 2012

Authors and Affiliations

  1. 1.Division of Pharmacology, Department of Biochemistry and Bioinformative SciencesSchool of Medicine, University of Fukui, Faculty of Medical SciencesFukuiJapan
  2. 2.School of Physiology and Pharmacology, Medical Sciences Building, University of BristolBristolUK

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