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Overview of Skeletal Repair (Fracture Healing and Its Assessment)

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Book cover Skeletal Development and Repair

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1130))

Abstract

The study of postnatal skeletal repair is of immense clinical interest. Optimal repair of skeletal tissue is necessary in all varieties of elective and reparative orthopedic surgical treatments. However, the repair of fractures is unique in this context in that fractures are one of the most common traumas that humans experience and are the end-point manifestation of osteoporosis, the most common chronic disease of aging. In the first part of this introduction the basic biology of fracture healing is presented. The second part discusses the primary methodological approaches that are used to examine repair of skeletal hard tissue and specific considerations for choosing among and implementing these approaches.

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Acknowledgments

This work is supported by NIH Grants AR056637 and AR062642.

Author information

Authors and Affiliations

  1. Boston University School of Medicine, Boston, MA, USA

    Elise F. Morgan, Anthony De Giacomo & Louis C. Gerstenfeld

Authors
  1. Elise F. Morgan
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  2. Anthony De Giacomo
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  3. Louis C. Gerstenfeld
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Editor information

Editors and Affiliations

  1. Department of Orthopedics and Rehabilita, University of Rochester Medical Center, Rochester, New York, USA

    Matthew J. Hilton

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Morgan, E.F., De Giacomo, A., Gerstenfeld, L.C. (2014). Overview of Skeletal Repair (Fracture Healing and Its Assessment). In: Hilton, M. (eds) Skeletal Development and Repair. Methods in Molecular Biology, vol 1130. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-989-5_2

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  • DOI: https://doi.org/10.1007/978-1-62703-989-5_2

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-988-8

  • Online ISBN: 978-1-62703-989-5

  • eBook Packages: Springer Protocols

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