Abstract
This chapter presents a method called PolyA-iEP that has been developed for the prediction of polyadenylation sites. More precisely, PolyA-iEP is a method that recognizes mRNA 3′ends which contain polyadenylation sites. It is a modular system which consists of two main components. The first exploits the advantages of emerging patterns and the second is a distance-based scoring method. The outputs of the two components are finally combined by a classifier. The final results reach very high scores of sensitivity and specificity.
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References
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Kavakiotis, I., Tzanis, G., Vlahavas, I. (2014). Polyadenylation Site Prediction Using PolyA-iEP Method. In: Rorbach, J., Bobrowicz, A. (eds) Polyadenylation. Methods in Molecular Biology, vol 1125. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-971-0_11
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DOI: https://doi.org/10.1007/978-1-62703-971-0_11
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Publisher Name: Humana Press, Totowa, NJ
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