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Molecular Diagnostics for Melanoma pp 3–9Cite as

Novel Insights/Translational Implication from the Emerging Biology of Melanoma

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1102))

Abstract

Melanoma is a main example of how applying advances in basic biology, pharmacology, and molecular diagnostics into the clinic results in unprecedented benefits to patients. After many years of lack of advances in the treatment of patients with metastatic melanoma, the advent of new therapies that block driver oncogenic signaling and modulate immune responses to cancer provided the first studies with a positive impact in overall survival (OS) of patients with advanced melanoma. The pace of progress in the treatment of this disease has been greatly accelerated by these initial breakthroughs, and it continues with new generation agents and combinatorial approaches.

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Author information

Authors and Affiliations

  1. Division of Hematology-Oncology, Department of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA

    Antoni Ribas

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  1. Antoni Ribas
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Editor information

Editors and Affiliations

  1. Cancer Diagnosis Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

    Magdalena Thurin

  2. Sidra Medical and Research Center,Qatar Foundation, Doha, Qatar

    Francesco M. Marincola

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Ribas, A. (2014). Novel Insights/Translational Implication from the Emerging Biology of Melanoma. In: Thurin, M., Marincola, F. (eds) Molecular Diagnostics for Melanoma. Methods in Molecular Biology, vol 1102. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-727-3_1

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  • DOI: https://doi.org/10.1007/978-1-62703-727-3_1

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-726-6

  • Online ISBN: 978-1-62703-727-3

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