Abstract
The detection of auto-antibodies detection is a major aspect of patient’s immunomonitoring. Antibodies directed against the heart and kidney Angiotensin II type 1 receptor (AT1R) play a major role in antibody mediated rejection after heart and kidney transplantation and in obliterative vasculopathy of autoimmune diseases. Here, a sandwich enzyme-linked immunosorbent assay (ELISA) is the reliable tool for the detection of auto-antibodies targeting AT1R.
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References
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Acknowledgments
We acknowledge Dr. Harald Heidecke, Dr. Kai Schulze-Förster (CellTrend GmbH, Luckenwalde), and Dr. Aurélie Philippe for their methodological inputs.
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Dragun, D. (2013). The Detection of Antibodies to the Angiotensin II-Type 1 Receptor in Transplantation. In: Zachary, A., Leffell, M. (eds) Transplantation Immunology. Methods in Molecular Biology, vol 1034. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-493-7_19
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DOI: https://doi.org/10.1007/978-1-62703-493-7_19
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-492-0
Online ISBN: 978-1-62703-493-7
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