Abstract
With novel genome-wide technologies it is nowadays possible to perform detailed molecular analyses of normal and malignant tissues. Acute myeloid leukemia (AML) is a heterogeneous group of diseases with variable response to therapy. Gene expression profiling and genome-wide genotyping have recently been successfully applied to unravel the heterogeneity of AML. This chapter gives instructions and recommendations for genome-wide gene expression analyses, genotyping, and copy number analyses, as performed for AML using Affymetrix GeneChips.
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Sanders, M.A., Valk, P.J.M. (2013). Genome-Wide Gene Expression Profiling, Genotyping, and Copy Number Analyses of Acute Myeloid Leukemia Using Affymetrix GeneChips. In: Innocenti, F., van Schaik, R. (eds) Pharmacogenomics. Methods in Molecular Biology, vol 1015. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-435-7_10
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DOI: https://doi.org/10.1007/978-1-62703-435-7_10
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