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Haemostasis pp 31–46Cite as

The Role of the Vessel Wall

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 992))

Abstract

The role of the vessel wall is complex and its effects are wide-ranging. The vessel wall, specifically the endothelial monolayer that lines the inner lumen, possesses the ability to influence various physiological states both locally and systemically by controlling vascular tone, basement membrane component synthesis, angiogenesis, haemostatic properties, and immunogenicity. This is an overview of the function and structure of the vessel wall and how disruption and dysfunction in any of these regulatory roles can lead to disease states.

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Acknowledgments

Anthony Chan is supported by the Bayer Thrombosis and Haemostasis Research Grant.

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Authors and Affiliations

  1. Thrombosis and Atherosclerosis Research Institute (TaARI), McMaster University, Hamilton, ON, Canada

    Nethnapha Paredes & Anthony K. C. Chan

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  1. Nethnapha Paredes
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  2. Anthony K. C. Chan
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Editors and Affiliations

  1. Department of Paediatrics, University of Melbourne, n/a, Parkville, 3052, Victoria, Australia

    Paul Monagle

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Paredes, N., Chan, A.K.C. (2013). The Role of the Vessel Wall. In: Monagle, P. (eds) Haemostasis. Methods in Molecular Biology, vol 992. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-339-8_3

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  • DOI: https://doi.org/10.1007/978-1-62703-339-8_3

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