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Droplet-Based Microfluidics

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Microfluidic Diagnostics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 949))

Abstract

Droplet-based microfluidics or digital microfluidics is a subclass of microfluidic devices, wherein droplets are generated using active or passive methods. The active method for generation of droplets involves the use of an external factor such as an electric field for droplet generation. Two techniques that fall in this category are dielectrophoresis (DEP) and electrowetting on dielectric (EWOD). In passive methods, the droplet generation depends on the geometry and dimensions of the device. T-junction and flow focusing methods are examples of passive methods used for generation of droplets. In this chapter the methods used for droplet generation, mixing of contents of droplets, and the manipulation of droplets are described in brief. A review of the applications of digital microfluidics with emphasis on the last decade is presented.

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Authors and Affiliations

  1. Institute of Biomedical Engineering & Department of Chemistry, Imperial College, London, UK

    Sanjiv Sharma, Steven Scott & Anthony Cass

  2. Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

    Monpichar Srisa-Art

  3. Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Hyderabad, Andhra Pradesh, India

    Amit Asthana

Authors
  1. Sanjiv Sharma
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  2. Monpichar Srisa-Art
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  3. Steven Scott
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  4. Amit Asthana
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  5. Anthony Cass
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Corresponding author

Correspondence to Sanjiv Sharma .

Editor information

Editors and Affiliations

  1. Key Laboratory for Organic Electronics &, Information Displays (KLOEID), Nanjing Univ. of Posts&Telecommunication, Jia Sheng Hua Yuan, No.2 Building Room 201, Nanjing, 210013, Jiangsu, China, People's Republic

    Gareth Jenkins

  2. Scientific & Medical Communications Cons, avenue Paul Santy 1C, Ecully, 69130, France

    Colin D. Mansfield

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Sharma, S., Srisa-Art, M., Scott, S., Asthana, A., Cass, A. (2013). Droplet-Based Microfluidics. In: Jenkins, G., Mansfield, C. (eds) Microfluidic Diagnostics. Methods in Molecular Biology, vol 949. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-134-9_15

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  • DOI: https://doi.org/10.1007/978-1-62703-134-9_15

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-133-2

  • Online ISBN: 978-1-62703-134-9

  • eBook Packages: Springer Protocols

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