Abstract
Sensitive skin is defined as the occurrence of erythema and/or abnormal stinging, burning, and tingling sensations (and sometimes as pain or pruritus) in response to multiple factors that may be physical (UV, heat, cold, wind), chemical (cosmetics, soaps, water, pollutants), psychological (stress), or hormonal (menstrual cycle). Because sensitive skins are defined as a response to multiple factors that may be physical and/or chemical, an abnormal activation of TRP channels appears probable. They can be studied using questionnaires or clinical tests with different stimuli. In vitro studies are also possible with co-cultures of neurons and skin cells mimicking neurogenic inflammation.
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Misery, L. (2012). Skin Sensitivity Studies. In: Szallasi, A., Bíró, T. (eds) TRP Channels in Drug Discovery. Methods in Pharmacology and Toxicology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-095-3_17
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DOI: https://doi.org/10.1007/978-1-62703-095-3_17
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Publisher Name: Humana Press, Totowa, NJ
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