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Development of an On-Site Measurement System for Salivary Stress-Related Substances Based on Microchip CE

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Clinical Applications of Capillary Electrophoresis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 919))

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Abstract

Secretory immunoglobulin A (sIgA) in saliva has been suggested to be a potential marker of chronic, long-term stress due to suppression of the immune system. A rapid point-of-care testing platform for stress measurement based on immunoassay and capillary electrophoresis (CE) separation was ­developed using a poly(methyl methacrylate) (PMMA) chip and a laboratory-built microchip CE system. A method for the quantitative determination of sIgA in human saliva is introduced.

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Correspondence to Yoshihide Tanaka .

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Tanaka, Y., Naruishi, N. (2013). Development of an On-Site Measurement System for Salivary Stress-Related Substances Based on Microchip CE. In: Phillips, T., Kalish, H. (eds) Clinical Applications of Capillary Electrophoresis. Methods in Molecular Biology, vol 919. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-029-8_6

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  • DOI: https://doi.org/10.1007/978-1-62703-029-8_6

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-028-1

  • Online ISBN: 978-1-62703-029-8

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