Abstract
Capillary electrophoresis is an analytical technique that separates ions based on their electrophoresis mobility with the use of an applied voltage. Capillary electrophoresis is used most predominantly in nuclear acid fragment analysis as well as DNA sequencing because it gives faster results and provides high resolution separation. Here we describe an application using capillary electrophoreses for screening the Fragile X expanded alleles to demonstrate the application
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Acknowledgments
This work was supported by ARUP Laboratories and reagents for validation were provided by Celera. We appreciate the efforts of Maria Bettinson, Mohammed Jama and Ping Yu in validating and preparing the procedure, and Anthony Adams for manuscript formatting.
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Mao, R., Bayrak-Toydemir, P., Lyon, E. (2013). Capillary Electrophoresis for the Detection of Fragile X Expanded Alleles. In: Phillips, T., Kalish, H. (eds) Clinical Applications of Capillary Electrophoresis. Methods in Molecular Biology, vol 919. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-029-8_24
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DOI: https://doi.org/10.1007/978-1-62703-029-8_24
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-028-1
Online ISBN: 978-1-62703-029-8
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