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Nanoparticles in Biology and Medicine pp 45–55Cite as

Gold Nanoparticle Antibody Conjugates for Use in Competitive Lateral Flow Assays

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 906))

Abstract

Gold nanoparticles (GNPs) are widely used in a variety of biomedical diagnostic assays and for imaging. Their popularity stems from key properties such as their low toxicity and high extinction coefficients, as well as straightforward synthesis methods that allow GNPs to be produced quickly and inexpensively. Here we describe the use of GNPs for visual detection in a lateral flow assay using benzodiazepine affinity assay to illustrate the methods

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Author information

Authors and Affiliations

  1. School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey, UK

    Julian Bailes & Mikhail Soloviev

  2. HFL Ltd., Fordham, Ely, Cambridgeshire, UK

    Samantha Mayoss & Phil Teale

Authors
  1. Julian Bailes
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  2. Samantha Mayoss
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  3. Phil Teale
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  4. Mikhail Soloviev
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Corresponding author

Correspondence to Mikhail Soloviev .

Editor information

Editors and Affiliations

  1. School of Biological Sciences, Royal Holloway University of London, Egham Hill, Egham, Surrey, TW20 0EX, United Kingdom

    Mikhail Soloviev

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Bailes, J., Mayoss, S., Teale, P., Soloviev, M. (2012). Gold Nanoparticle Antibody Conjugates for Use in Competitive Lateral Flow Assays. In: Soloviev, M. (eds) Nanoparticles in Biology and Medicine. Methods in Molecular Biology, vol 906. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-953-2_4

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  • DOI: https://doi.org/10.1007/978-1-61779-953-2_4

  • Published:

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-952-5

  • Online ISBN: 978-1-61779-953-2

  • eBook Packages: Springer Protocols

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