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Vector Systems for Prenatal Gene Therapy: Choosing Vectors for Different Applications

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Book cover Prenatal Gene Therapy

Part of the book series: Methods in Molecular Biology ((MIMB,volume 891))

Abstract

This chapter gives a comparative review of the different vector systems applied to date in prenatal gene therapy experiments highlighting the need for versatility and choice for application in accordance with the actual aim of the study. It reviews the key characteristics of the four main gene therapy vector systems and gives examples for their successful application in prenatal gene therapy experiments.

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Author information

Authors and Affiliations

  1. National Heart and Lung Institute, Molecular and Cellular Medicine Section, Imperial College London, London, UK

    Charles Coutelle MD, DSc

  2. Institute for Women’s Health, Gene Transfer Technology Group, University College London, London, UK

    Simon N. Waddington PhD

Authors
  1. Charles Coutelle MD, DSc
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  2. Simon N. Waddington PhD
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Corresponding author

Correspondence to Charles Coutelle MD, DSc .

Editor information

Editors and Affiliations

  1. National Heart & Lung Inst., Molecular & Cellular Medicine Sec., Imperial College London, Imperial College Road, London, SW7 2AZ, United Kingdom

    Charles Coutelle

  2. Reader in Gene Transfer Technology, Gene Transfer Technology Group, University College London, Chenies Mews 86-96, London, WC1E 6HX, United Kingdom

    Simon N. Waddington

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Coutelle, C., Waddington, S.N. (2012). Vector Systems for Prenatal Gene Therapy: Choosing Vectors for Different Applications. In: Coutelle, C., Waddington, S. (eds) Prenatal Gene Therapy. Methods in Molecular Biology, vol 891. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-873-3_3

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  • DOI: https://doi.org/10.1007/978-1-61779-873-3_3

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-872-6

  • Online ISBN: 978-1-61779-873-3

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