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Xenotransplantation: An Overview of the Field

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 885))

Abstract

Xenotransplantation, the transplantation of cells, tissues, or organs between different species, has the potential to overcome the current shortage of human organs and tissues for transplantation. In the last decade, the progress made in the field is remarkable, suggesting that clinical xenotransplantation procedures, particularly those involving cells, may become a reality in the not-too-distant future. However, several hurdles remain, mainly immunological barriers, physiological discrepancies, and safety issues, making xenotransplantion a complex and multidisciplinary discipline.

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Acknowledgments

The authors would like to thank the EU FP6 Integrated Project “Xenome” (www.xenome.eu), contract n° LSHB-CT-2006-037377 and the Consortium for Research in Organ Transplantation (CORIT, Padua, Italy) for their support. Special thanks to Dr. Michela Seveso, Dr. Marta Vadori, and Dr Federica Besenzon for their review of the manuscript.

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Correspondence to Emanuele Cozzi .

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Tisato, V., Cozzi, E. (2012). Xenotransplantation: An Overview of the Field. In: Costa, C., Máñez, R. (eds) Xenotransplantation. Methods in Molecular Biology, vol 885. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-845-0_1

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  • DOI: https://doi.org/10.1007/978-1-61779-845-0_1

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