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Animal Models of Acute Neurological Injuries II pp 313–330Cite as

Electrophysiological Approaches in Traumatic Brain Injury

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Abstract

This chapter briefly reviews electrophysiological applications in experimental models of traumatic brain injury (TBI). The review was restricted to studies where rodents were used in one of the more common in vivo models of TBI and where electrophysiological recordings were then conducted either in vivo or in brain slices. This summary discussion is intended for researchers new to the topic of electrophysiology in TBI, who may be interested in knowing which specific recording techniques have been adapted in the various models. The chapter concludes with a protocol for recording compound action potentials in the corpus callosum of rats which have previously undergone fluid percussion TBI.

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Acknowledgments

Supported by NIH research grants NS-057758 (TMR), and by a Virginia Commonwealth Neurotrauma Initiative Award 07-302F (TMR).

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Authors and Affiliations

  1. Department of Anatomy and Neurobiology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA, USA

    Thomas M. Reeves & Beverly S. Colley

Authors
  1. Thomas M. Reeves
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  2. Beverly S. Colley
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Corresponding author

Correspondence to Thomas M. Reeves .

Editor information

Editors and Affiliations

  1. School of Medicine, University of Pittsburgh, Terrace St. 3500, Pittsburgh, 15213, Pennsylvania, USA

    Jun Chen

  2. School of Medicine, Stark Neurosciences Res. Inst., Indiana University, W. Walnut St. 950, Indianapolis, 46202, Indiana, USA

    Xiao-Ming Xu

  3. School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Barnhill Dr. 635, Indianapolis, 46202, Indiana, USA

    Zao C. Xu

  4. School of Medicine, Dept. Neurosurgery, Loma Linda University, Anderson St. 11234, Loma Linda, 92354, California, USA

    John H. Zhang

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Reeves, T.M., Colley, B.S. (2012). Electrophysiological Approaches in Traumatic Brain Injury. In: Chen, J., Xu, XM., Xu, Z., Zhang, J. (eds) Animal Models of Acute Neurological Injuries II. Springer Protocols Handbooks. Humana Press. https://doi.org/10.1007/978-1-61779-782-8_30

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  • DOI: https://doi.org/10.1007/978-1-61779-782-8_30

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-781-1

  • Online ISBN: 978-1-61779-782-8

  • eBook Packages: Springer Protocols

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