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Three-Dimensional Microfabrication by Two-Photon Polymerization Technique

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Book cover Computer-Aided Tissue Engineering

Part of the book series: Methods in Molecular Biology ((MIMB,volume 868))

Abstract

Two-photon polymerization (2PP) technique is a novel CAD/CAM-based technology allowing the fabrication of any computer-designed 3D structure from a photosensitive polymeric material with a lateral resolution down to 100 nm. The fabrication of highly reproducible scaffold structures for tissue engineering by 2PP is very important for systematic studies of cellular processes and better understanding of in vitro tissue formation. Flexibility of this technology and ability to precisely define 3D construct geometry allow the direct addressing of issues associated with vascularization and patient-specific tissue fabrication. In this chapter, we report on our recent advances in the fabrication of biomedical implants and 3D scaffolds for tissue engineering and regenerative medicine by 2PP technique.

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Acknowledgments

The authors gratefully acknowledge very important contribution from their colleagues, who have been involved in different parts of this work: A. Doraiswamy, A. Haverich, R. Narayan, A. Ngezahayo, A. Ostendorf, and S. Schlie. Financial support from the DFG Excellence Cluster “ReBirth” and Transregio TR37 project is gratefully acknowledged.

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Authors and Affiliations

  1. Institut für Werkstoffwissenschaft und Werkstofftechnologie (E308), TU Wien, Wien, Austria

    Aleksandr Ovsianikov

  2. Nanotechnology Department, Laser Zentrum Hannover e.V., Hannover, Germany

    Boris N. Chichkov

Authors
  1. Aleksandr Ovsianikov
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  2. Boris N. Chichkov
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Correspondence to Aleksandr Ovsianikov .

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Editors and Affiliations

  1. , Department of Neurosurgery, Baylor College of Medicine, Holcombe Blvd. 2002, Houston, 77030, Texas, USA

    Michael A.K. Liebschner

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Ovsianikov, A., Chichkov, B.N. (2012). Three-Dimensional Microfabrication by Two-Photon Polymerization Technique. In: Liebschner, M. (eds) Computer-Aided Tissue Engineering. Methods in Molecular Biology, vol 868. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-764-4_19

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  • DOI: https://doi.org/10.1007/978-1-61779-764-4_19

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-763-7

  • Online ISBN: 978-1-61779-764-4

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