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Imaging of Hematoma and Perihematomal Edema in Experimental Intracerebral Hemorrhage

  • Protocol
  • First Online:
Animal Models of Acute Neurological Injuries II

Part of the book series: Springer Protocols Handbooks ((SPH))

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Abstract

The aim is to outline how experimental intracerebral hematoma and perihematomal edema can be imaged. For postmortem investigation of the clot, morphometric analysis, spectrophotometry, and magnetic resonance imaging (MRI) are used. The edema in sacrificed animals is determined by the brain water content. In living animals, MRI is the imaging modality of choice for visualization of hematoma and edema.

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Georg-August-University Göttingen, Göttingen, Germany

    Veit Rohde

  2. Department of Neuropathology, Georg-August-University Göttingen, Göttingen, Germany

    Walter Schulz-Schäffer

  3. Department of Neuroradiology, University of Toronto, Toronto, ON, Canada

    Timo Krings

Authors
  1. Veit Rohde
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  2. Walter Schulz-Schäffer
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  3. Timo Krings
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Corresponding author

Correspondence to Veit Rohde .

Editor information

Editors and Affiliations

  1. School of Medicine, University of Pittsburgh, Terrace St. 3500, Pittsburgh, 15213, Pennsylvania, USA

    Jun Chen

  2. School of Medicine, Stark Neurosciences Res. Inst., Indiana University, W. Walnut St. 950, Indianapolis, 46202, Indiana, USA

    Xiao-Ming Xu

  3. School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Barnhill Dr. 635, Indianapolis, 46202, Indiana, USA

    Zao C. Xu

  4. School of Medicine, Dept. Neurosurgery, Loma Linda University, Anderson St. 11234, Loma Linda, 92354, California, USA

    John H. Zhang

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Rohde, V., Schulz-Schäffer, W., Krings, T. (2012). Imaging of Hematoma and Perihematomal Edema in Experimental Intracerebral Hemorrhage. In: Chen, J., Xu, XM., Xu, Z., Zhang, J. (eds) Animal Models of Acute Neurological Injuries II. Springer Protocols Handbooks. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-576-3_56

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  • DOI: https://doi.org/10.1007/978-1-61779-576-3_56

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-575-6

  • Online ISBN: 978-1-61779-576-3

  • eBook Packages: Springer Protocols

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