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Ion Channel Assessment

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Animal Models of Acute Neurological Injuries II

Part of the book series: Springer Protocols Handbooks ((SPH))

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Abstract

Molecular mechanisms underlying subarachnoid hemorrhage (SAH)-induced cerebral vasospasm are complex and still partially unknown. Molecular-biological studies and clinical trials support a central role of ion channels, but further detailed studies have to evaluate their exact role during vasospasm following SAH.

This chapter focuses on methods and principles of ion channel assessment which includes the wide-spread spectrum of molecular-biological, electrophysiological, immunochemical, and functional methods.

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Acknowledgment

We want to thank Prof. Toni Schneider for his constant support (Institute of Neurophysiology, University of Cologne, Germany).

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Authors and Affiliations

  1. Klinik für Neurochirurgie, Heinrich-Heine-Universität, Düsseldorf, Germany

    Marcel Alexander Kamp, Hans-Jakob Steiger & Daniel Hänggi

Authors
  1. Marcel Alexander Kamp
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  2. Hans-Jakob Steiger
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  3. Daniel Hänggi
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Corresponding author

Correspondence to Daniel Hänggi .

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Editors and Affiliations

  1. School of Medicine, University of Pittsburgh, Terrace St. 3500, Pittsburgh, 15213, Pennsylvania, USA

    Jun Chen

  2. School of Medicine, Stark Neurosciences Res. Inst., Indiana University, W. Walnut St. 950, Indianapolis, 46202, Indiana, USA

    Xiao-Ming Xu

  3. School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Barnhill Dr. 635, Indianapolis, 46202, Indiana, USA

    Zao C. Xu

  4. School of Medicine, Dept. Neurosurgery, Loma Linda University, Anderson St. 11234, Loma Linda, 92354, California, USA

    John H. Zhang

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Kamp, M.A., Steiger, HJ., Hänggi, D. (2012). Ion Channel Assessment. In: Chen, J., Xu, XM., Xu, Z., Zhang, J. (eds) Animal Models of Acute Neurological Injuries II. Springer Protocols Handbooks. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-576-3_42

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  • DOI: https://doi.org/10.1007/978-1-61779-576-3_42

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-575-6

  • Online ISBN: 978-1-61779-576-3

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