Abstract
Cancer Stem cells (CSCs) are the source of many solid tumor types including hepatocellular carcinoma. MicroRNAs (miRNAs) are small noncoding RNAs and have been showed to be associated with hepatic CSCs. Here, we described methods to screen hepatic CSC-related miRNAs, and to validate and examine their expressions and functions in vitro and in vivo, which contribute to the maintenance of stemness and differentiation of hepatic CSCs.
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Acknowledgment
This work was supported by the Intramural Research Program of the Center for Cancer Research, the National Cancer Institute (Z01 BC 010313 and Z01 BC 010876).
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Ji, J., Wang, X.W. (2012). Identification of Cancer Stem Cell-Related MicroRNAs in Hepatocellular Carcinoma. In: Ochiya, T. (eds) Liver Stem Cells. Methods in Molecular Biology, vol 826. Springer, New York, NY. https://doi.org/10.1007/978-1-61779-468-1_14
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DOI: https://doi.org/10.1007/978-1-61779-468-1_14
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