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Psychiatric Disorders pp 145–153Cite as

Behavioral Model for Assessing Cognitive Decline

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 829))

Abstract

The water maze task can be used to assess sensory motor and cognitive function in rodents. When properly employed, this task can behaviorally assess acquisition of a spatial search strategy, as well as working and reference memory. The following section uses research on age-related, cognitive decline to illustrate the methods employed and highlight areas that can, if not properly controlled, confound a study.

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Author information

Authors and Affiliations

  1. Max Planck Institute of Psychiatry, Proteomics, and Biomarkers, Munich, Germany

    Michael Guidi

  2. Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, FL, USA

    Thomas C. Foster

Authors
  1. Michael Guidi
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  2. Thomas C. Foster
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Corresponding author

Correspondence to Thomas C. Foster .

Editor information

Editors and Affiliations

  1. McKnight Brain Institute, Department of Psychiatry, University of Florida, S. Newell Dr. 100, Gainesville, 32610, Florida, USA

    Firas H. Kobeissy

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Guidi, M., Foster, T.C. (2012). Behavioral Model for Assessing Cognitive Decline. In: Kobeissy, F. (eds) Psychiatric Disorders. Methods in Molecular Biology, vol 829. Humana Press. https://doi.org/10.1007/978-1-61779-458-2_8

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  • DOI: https://doi.org/10.1007/978-1-61779-458-2_8

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-457-5

  • Online ISBN: 978-1-61779-458-2

  • eBook Packages: Springer Protocols

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