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In vivo NMR Imaging pp 205–226Cite as

Hyperpolarized Molecules in Solution

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 771))

Abstract

Hyperpolarization is a technique to enhance the nuclear polarization and thereby increase the available signal in magnetic resonance (MR). This chapter provides an introduction to the concept of hyperpolarization as well as an overview of dynamic nuclear polarization (DNP) and para-hydrogen induced polarization (PHIP), two methods used to generate hyperpolarized molecules in aqueous solution.

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Author information

Authors and Affiliations

  1. GE Healthcare, 1808, Frederiksberg C, Denmark

    Jan Henrik Ardenkjaer-Larsen

  2. REAC Fuel AB, 223 63, Lund, Sweden

    Haukur Jóhannesson

  3. GE Healthcare, P.O.Box 314, 17175, Stockholm, Sweden

    J. Stefan Petersson

  4. GE Healthcare, HP7 9LL, Amersham, UK

    Jan Wolber

Authors
  1. Jan Henrik Ardenkjaer-Larsen
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  2. Haukur Jóhannesson
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  3. J. Stefan Petersson
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  4. Jan Wolber
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Correspondence to Jan Henrik Ardenkjaer-Larsen .

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Editors and Affiliations

  1. ERC Project BiosensorImaging, Leibniz-Institut für Molekulare Pharmako, Robert-Roessle-Str. 10, Berlin, 13125, Germany

    Leif Schröder

  2. Inst. Klinische Radiologie, AG Experimentelle, Universität Münster, Haus Rosenbach Waldeyerstr. 1, Münster, 48149, Germany

    Cornelius Faber

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Ardenkjaer-Larsen, J.H., Jóhannesson, H., Petersson, J.S., Wolber, J. (2011). Hyperpolarized Molecules in Solution. In: Schröder, L., Faber, C. (eds) In vivo NMR Imaging. Methods in Molecular Biology, vol 771. Humana Press. https://doi.org/10.1007/978-1-61779-219-9_11

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