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Biomedical Nanotechnology pp 223–241Cite as

Applications of Carbon Nanotubes in Biomedical Studies

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 726))

Abstract

Carbon nanotubes (CNTs) are novel, one-dimensional nanomaterials with many unique physical and chemical properties that have been increasingly explored for biological and biomedical applications. In this chapter, we briefly summarize the intrinsic properties of single-walled carbon nanotubes (SWNTs), a special class of CNTs, and their corresponding applications in these fields. SWNTs have been utilized for the ultrasensitive detection of biological species, providing a label-free approach. SWNT-Raman tags have achieved detection sensitivity down to 1 fmol/L. SWNT-based drug delivery systems have shown promising potential based on preliminary in vitro and in vivo studies. Also, the remarkable optical properties of SWNTs have made them promising candidates as contrast agents for imaging in cells and animals. Moreover, due to their excellent mechanical strength, SWNTs have been used to improve the mechanical properties of solid polymeric nanocomposites and porous scaffolds. Sample preparation procedures for the use of SWNTs as fluorescent imaging labels and in biological composites will be discussed.

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Acknowledgments

The authors would like to thank Jarrett Leeds for helping in the preparation of soluble SWNT. This work was supported by Office of the Vice President of Research at Stony Brook University (SB).

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  1. Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, USA

    Hongwei Liao

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  1. Hongwei Liao
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  2. Bhavna Paratala
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  3. Balaji Sitharaman
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  4. Yuhuang Wang
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Correspondence to Hongwei Liao .

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  1. Center for Nanoscale Materials, Argonne National Laboratory, S. Cass Avenue 9700, Argonne, 60439, Illinois, USA

    Sarah J. Hurst

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Liao, H., Paratala, B., Sitharaman, B., Wang, Y. (2011). Applications of Carbon Nanotubes in Biomedical Studies. In: Hurst, S. (eds) Biomedical Nanotechnology. Methods in Molecular Biology, vol 726. Humana Press. https://doi.org/10.1007/978-1-61779-052-2_15

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