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LC/MS Data Processing for Label-Free Quantitative Analysis

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Data Mining in Proteomics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 696))

Abstract

In this chapter, we describe the use of SuperHirn and MSight, two complementary tools developed to the processing of label-free LC/MS data in view of the quantitation of proteomics samples. While MSight is mainly dedicated to the visualisation and navigation into LC/MS data, SuperHirn is specialised in peak detection, normalisation and alignment of LC/MS runs. These two tools can be used in a complementary way and one of the possible usages is described here.

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Acknowledgment

MSight was partially funded by EU project LOCCANDIA (FP6-2004-IST-5 # 034202).

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Palagi, P.M., Müller, M., Walther, D., Lisacek, F. (2011). LC/MS Data Processing for Label-Free Quantitative Analysis. In: Hamacher, M., Eisenacher, M., Stephan, C. (eds) Data Mining in Proteomics. Methods in Molecular Biology, vol 696. Humana Press. https://doi.org/10.1007/978-1-60761-987-1_24

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  • DOI: https://doi.org/10.1007/978-1-60761-987-1_24

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60761-986-4

  • Online ISBN: 978-1-60761-987-1

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