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Detection of Bacterial Signaling Molecules in Liquid or Gaseous Environments

  • Peter EdmonsonEmail author
  • Desmond Stubbs
  • William Hunt
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 692)

Abstract

The detection of bacterial signaling molecules in liquid or gaseous environments has been occurring in nature for billions of years. More recently, man-made materials and systems has also allowed for the detection of small molecules in liquid or gaseous environments. This chapter will outline some examples of these man-made detection systems by detailing several acoustic-wave sensor systems applicable to quorum sensing. More importantly though, a comparison will be made between existing bacterial quorum sensing signaling systems, such as the Vibrio harveyi two-component system and that of man-made detection systems, such as acoustic-wave sensor systems and digital communication receivers similar to those used in simple cell phone technology.

It will be demonstrated that the system block diagrams for either bacterial quorum sensing systems or man-made detection systems are all very similar, and that the established modeling techniques for digital communications and acoustic-wave sensors can also be transformed to quorum sensing systems.

Key words

Acoustic wave biosensors State-space mapping RFID/biosensors Chemically orthogonal antibodies Antibody promiscuity Vibrio harveyi two-component model 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Zen Sensing LLC.DecaturUSA

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