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Behavioral Validation in Animal Models of Dementia

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Animal Models of Dementia

Part of the book series: Neuromethods ((NM,volume 48))

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Abstract

The development of complex disease models requires the parallel development or optimization of valid behavioral paradigms assessing complex brain-behavior relations. Besides validity of the applied paradigm, standardization at the level of experimental animals, testing procedures, and surroundings is essential to generate reliable data. High levels of validity and standardization can be reached only by skilled and experienced researchers. This chapter summarizes the most frequently used cognitive and behavioral paradigms in the phenotyping of rodent models of dementia.

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Author information

Authors and Affiliations

  1. Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Belgium

    Debby Van Dam, Annemie Van Dijck & Peter Paul De Deyn

  2. Department of Neurology, Middelheim Hospital, ZNA, Antwerp, Belgium

    Peter Paul De Deyn

Authors
  1. Debby Van Dam
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  2. Annemie Van Dijck
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  3. Peter Paul De Deyn
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Editor information

Editors and Affiliations

  1. Institute Born-Bunge, Lab of Neurochemistry & Behaviour, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610, Belgium

    Peter Paul De Deyn

  2. Institute Born-Bunge, Lab of Neurochemistry & Behaviour, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610, Belgium

    Debby Van Dam

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© 2011 Springer Science+Business Media, LLC

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Van Dam, D., Van Dijck, A., De Deyn, P.P. (2011). Behavioral Validation in Animal Models of Dementia. In: De Deyn, P., Van Dam, D. (eds) Animal Models of Dementia. Neuromethods, vol 48. Humana Press. https://doi.org/10.1007/978-1-60761-898-0_8

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  • DOI: https://doi.org/10.1007/978-1-60761-898-0_8

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60761-897-3

  • Online ISBN: 978-1-60761-898-0

  • eBook Packages: Springer Protocols

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