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Diagnostic Virology Protocols pp 101–121Cite as

Molecular Detection of Herpesviruses

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 665))

Abstract

In routine molecular diagnostics, detection of herpesviruses has made a major impact. Infection with herpesviruses is indicated by demonstrating the presence of the virus in selected specimens. Rapid and reliable detection of herpesvirus DNA helps to decrease the lethality as well as the sequelae of herpesvirus infection in patients at risk. This chapter discusses specimen types and both laboratory-developed and commercially available assays useful for molecular detection of herpesviruses. To meet the need for reliable laboratory results, it is advisable to employ maximum automated and standardized kits based on reagents and standards of reproducible high quality. In the routine diagnostic laboratory, introduction of IVD/CE and/or FDA-labeled tests is preferred.

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Authors and Affiliations

  1. Molecular Diagnostics Laboratory, IHMEM, Medical University of Graz, Graz, Austria

    Harald H. Kessler & Sophie Heyszl

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  1. Harald H. Kessler
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  2. Sophie Heyszl
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  1. , Research & Development Division, Health Protection Agency, High Holborn 330, London, WC1V 7BA, United Kingdom

    John R. Stephenson

  2. Northwick Park Hospital, Research and Development, North West London Hospitals NHS Trust, Watford Road, Harrow, HA13UJ, Middlesex, United Kingdom

    Alan Warnes

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Kessler, H.H., Heyszl, S. (2010). Molecular Detection of Herpesviruses. In: Stephenson, J., Warnes, A. (eds) Diagnostic Virology Protocols. Methods in Molecular Biology, vol 665. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-817-1_7

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  • DOI: https://doi.org/10.1007/978-1-60761-817-1_7

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-816-4

  • Online ISBN: 978-1-60761-817-1

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