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RNAi and microRNA-Mediated Gene Regulation in Stem Cells pp 15–25Cite as

A Brief Introduction to RNAi and MicroRNAs in Stem Cells

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 650))

Abstract

Recently, RNAi, including microRNAs (miRNAs), has become an important tool to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short chapter, we will give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We will also discuss RNAi as a tool to study stem cell function and the potential future practical applications.

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Authors and Affiliations

  1. Department of Physiology, East Carolina University, School of Medicine, Greenville, NC, USA

    Alexander K. Murashov

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  1. Alexander K. Murashov
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  1. Dept. Biology, East Carolina University, Greenville, 27858-4353, North Carolina, USA

    Baohong Zhang

  2. Dept. Biology, East Carolina University, Greenville, 27858-4353, North Carolina, USA

    Edmund J. Stellwag

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Murashov, A.K. (2010). A Brief Introduction to RNAi and MicroRNAs in Stem Cells. In: Zhang, B., Stellwag, E. (eds) RNAi and microRNA-Mediated Gene Regulation in Stem Cells. Methods in Molecular Biology, vol 650. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-769-3_2

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  • DOI: https://doi.org/10.1007/978-1-60761-769-3_2

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-768-6

  • Online ISBN: 978-1-60761-769-3

  • eBook Packages: Springer Protocols

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