Abstract
We describe herein PROTIS, a software package that allows for the combination of urine biomarkers (proteins, small molecules, cells) to provide accurate diagnostic information on renal disease states. Such an approach exemplifies the advantage conferred by using multiple markers, and can be generalized for identification of biomarker signatures to separate distinct sample groups.
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References
Hofmann W, Guder W (1989) A diagnostic programme for quantitative analysis of proteinuria. J Clin Chem Clin Biochem 27, 589–600
Ivandic M, Hofmann W, Guder WG (1996) Development and evaluation of a urine protein expert system. Clin Chem 42, 1214–1222
Kouri T, Fogazzi G, Gant V, Hallander H, Hofmann W, Guder WG (2000) European urinalysis guidelines. Scand J Clin Lab Invest 60(Supp 231) 1–96
Hofmann W, Ruth D, Guder W (2003) Urine protein differentiation and Protis, a new expert system for its interpretation. Riv Med Lab-JLM 4, 67–68
Dati F, Metzmann E (2005) Proteins. Labo-ratory testing and clinical use. Publisher: Diasys 279–295
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Hofmann, W., Sedlmeir-Hofmann, C., Ivandic´, M., Ruth, D., Luppa, P. (2010). PROTIS: Use of Combined Biomarkers for Providing Diagnostic Information on Disease States. In: Rai, A. (eds) The Urinary Proteome. Methods in Molecular Biology, vol 641. Humana Press. https://doi.org/10.1007/978-1-60761-711-2_8
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DOI: https://doi.org/10.1007/978-1-60761-711-2_8
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Publisher Name: Humana Press
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Online ISBN: 978-1-60761-711-2
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