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Vaccine Adjuvants pp 103–116Cite as

Adjuvant Activity on Human Cells In Vitro

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 626))

Abstract

Efficient vaccines against intracellular microbes or tumors will be based on innovative adjuvants able to induce efficient activation of dendritic cells. Indeed, natural or synthetic products activating Toll-like receptors (TLR) on dendritic cells (DCs) are currently in development for this purpose. Herein, we describe in vitro assays on human cells which might be useful for the preclinical screening and assessment of potential DC activators.

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Authors and Affiliations

  1. Institut d’Immunologie Médicale, Université Libre de Bruxelles, Charleroi, Belgium

    Dominique De Wit & Michel Goldman

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  1. Dominique De Wit
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  2. Michel Goldman
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Corresponding author

Correspondence to Dominique De Wit .

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Editors and Affiliations

  1. Dept. Cardio & Vascular Sciences, St. George's University of London, Cranmer Terrace, London, SW17 0RE, United Kingdom

    Gwyn Davies

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De Wit, D., Goldman, M. (2010). Adjuvant Activity on Human Cells In Vitro. In: Davies, G. (eds) Vaccine Adjuvants. Methods in Molecular Biology, vol 626. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-585-9_8

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  • DOI: https://doi.org/10.1007/978-1-60761-585-9_8

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-584-2

  • Online ISBN: 978-1-60761-585-9

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