Abstract
Dynamic cellular responses to carbon nanotubes were monitored by a real-time cell electronic sensing assay. This approach is based on the parallel impedance measurement of attached cells using electronic sensors integrated in wells of 96-well E-plate. It measures the real-time multiparameter index of cell growth named cell index (CI), which reflects the cell proliferation, morphology, attachment, and spreading. The label-free, real-time, and high-throughput assay overcomes many drawbacks in current optical based cytotoxicity assays in carbon nanotubes research, and enables dynamic monitoring of cellular responses to carbon nanotubes.
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Mu, Q., Zhai, S., Yan, B. (2010). Real-Time Monitoring of Cellular Responses to Carbon Nanotubes. In: Balasubramanian, K., Burghard, M. (eds) Carbon Nanotubes. Methods in Molecular Biology, vol 625. Humana Press. https://doi.org/10.1007/978-1-60761-579-8_8
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DOI: https://doi.org/10.1007/978-1-60761-579-8_8
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