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Advanced Protocols in Oxidative Stress II pp 427–434Cite as

Meta-Analysis: Drawing Conclusions When Study Results Vary

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 594))

Summary

Low-dose aspirin has been suggested to positively impact a number of clinical outcomes associated with oxidative stress; however, results of clinical trials surrounding its effect on a woman’s ability to achieve and sustain pregnancy have been inconclusive. A meta-analysis is an advantageous tool in this situation. Meta-analyses allow researchers to formally and systematically pool together all relevant research in order to clarify findings and form conclusions based on all currently available information. The purpose of this chapter is to describe how to perform a meta-analysis, clarify the impact of model selection, and provide examples of implementation.

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Author information

Authors and Affiliations

  1. Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD, USA

    Leslie Rosenthal & Enrique Schisterman

Authors
  1. Leslie Rosenthal
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  2. Enrique Schisterman
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Corresponding author

Correspondence to Enrique Schisterman .

Editor information

Editors and Affiliations

  1. Golden Leaf Rd. 215, Mars Hill, 28754, USA

    Donald Armstrong

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© 2010 Humana Press, a part of Springer Science+Business Media, LLC

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Rosenthal, L., Schisterman, E. (2010). Meta-Analysis: Drawing Conclusions When Study Results Vary. In: Armstrong, D. (eds) Advanced Protocols in Oxidative Stress II. Methods in Molecular Biology, vol 594. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-411-1_30

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  • DOI: https://doi.org/10.1007/978-1-60761-411-1_30

  • Published:

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-410-4

  • Online ISBN: 978-1-60761-411-1

  • eBook Packages: Springer Protocols

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