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Cardiovascular Genomics pp 157–173Cite as

QTL Mapping in Intercross and Backcross Populations

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Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 573))

Abstract

In the past two decades, various statistical approaches have been developed to identify quantitative trait locus with experimental organisms. In this chapter, we introduce several commonly used QTL mapping methods for intercross and backcross populations. Important issues related to QTL mapping, such as threshold and confidence interval calculations are also discussed. We list and describe five public domain QTL software packages commonly used by biologists.

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Author information

Authors and Affiliations

  1. Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA

    Fei Zou

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  1. Fei Zou
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Editors and Affiliations

  1. Research, Novartis Institute for Biomedical, Health Plaza 1, East Hanover, 07936, U.S.A.

    Keith DiPetrillo

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Zou, F. (2009). QTL Mapping in Intercross and Backcross Populations. In: DiPetrillo, K. (eds) Cardiovascular Genomics. Methods in Molecular Biology™, vol 573. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-247-6_9

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  • DOI: https://doi.org/10.1007/978-1-60761-247-6_9

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-246-9

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