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Piezoelectric Quartz Crystal Resonators Applied for Immunosensing and Affinity Interaction Studies

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Biosensors and Biodetection

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 504))

Summary

Piezoelectric quartz crystals serve as resonator-based transducers for direct and real-time monitoring of immunoaffinity interactions. The measuring system is briefly characterized; several examples for immobilization of antibodies are recommended. The piezoelectric immunoassays employing direct, competitive, and displacement-based formats are demonstrated on examples. The method for kinetic characterization of immunoaffinity interactions is presented.

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Author information

Authors and Affiliations

  1. Department of Biochemistry, Masaryk University, Brno, Czech Republic

    Petr Skládal

Authors
  1. Petr Skládal
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Editor information

Editors and Affiliations

  1. FDA Center for Devices and Radiological Health, Silver Spring, MD, USA

    Avraham Rasooly

  2. National Cancer Institute, Bethesda, MD, USA

    Avraham Rasooly

  3. Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA

    Keith E. Herold

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© 2009 Springer Science+Business Media, LLC

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Skládal, P. (2009). Piezoelectric Quartz Crystal Resonators Applied for Immunosensing and Affinity Interaction Studies. In: Rasooly, A., Herold, K.E. (eds) Biosensors and Biodetection. Methods in Molecular Biology™, vol 504. Humana Press. https://doi.org/10.1007/978-1-60327-569-9_3

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  • DOI: https://doi.org/10.1007/978-1-60327-569-9_3

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-568-2

  • Online ISBN: 978-1-60327-569-9

  • eBook Packages: Springer Protocols

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