Abstract
The polyamines spermidine [NH2(CH2)3NH(CH2)4NH2] and spermine [NH2(CH2)3NH(CH2)4NH(CH2)3NH2] and their diamine precursor, putrescine [NH2(CH2)4NH2], have been the subject of intense study relative to their potential as tumor markers during the past decade (1). These compounds have been implicated in numerous biochemical reactions and have been clearly associated with cellular growth processes. A number of publications have reviewed our present knowledge regarding these compounds, including their relationship to human disease (2–6).
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References
Marton, L. J., and Seidenfeld, J., Approaches to the study of polyamines as cancer markers, Polyamines in Biology and Medicine, Dekker, New York, in press.
Cohen, S. S., Introduction to the Polyamines, Prentice-Hall, Englewood Cliffs, NJ, 1971.
Bachrach, U., Function of Naturally Occurring Polyamines, Academic Press, New York, 1973.
Russell, D. H., ed., Polyamines in Normal and Neoplastic Growth, Raven Press, New York, 1973.
Campbell, R. A., Morris, D. R., Bartos, D., Daves, G. D., and Bartos, F., eds., Advances in Polyamine Research, Vols. 1 and 2 Raven Press, New York, 1978.
Morris, D. R., and Marton, L. J., eds., Polyamines in Biology and Medicine, Dekker, New York, in press.
Marton, L. J., Edward, M. S., Levin, V. A., Lubich, W. P., and Wilson, C. B., Cancer Res. 39, 993 (1979).
Marton, L. J., Edward, M. S., Levin, V. A., Lubich, W. P., and Wilson, C. B., CSF Polyamines: A new and important means of monitoring medulloblastoma. Cancer, in press.
Seiler, N., Clin. Chem. 23, 1519 (1977).
Bachrach, U., Analytical methods for polyamines, in Advances in Polyamine Research, vol. 2, Campbell, R. A., et al., eds., Raven Press, New York, 1978, p. 5.
Tabor, H., Tabor, C. W., and Irreverre, R., Anal. Biochem. 55, 457 (1973).
Bachrach, U., and Reches, B., Anal. Biochem. 17, 38 (1966).
Harik, S. I., Pasternak, G. W., and Snyder, S. H., Biochim. Biophys. Acta 304, 753 (1973).
Harik, S. I., and Marton, L. J., Arch. Neurol in press.
Marton, L. J., Heby, O., Levin, V. A., Lubich, W. P., Crafts, D. C., and Wilson, C. B., Cancer Res. 36, 973 (1976).
Bartos, D., Campbell, R. A., Bartos, F., and Grettie, D. P., Cancer Res. 35, 2056 (1975).
Bartos, F., Bartos, D., Dolney, A. M., Grettie, D. P., and Campbell, R. A., Res. Commun. Chem. Path. Pharm. 19, 295 (1978).
Campbell, R. A., Grettie, D. P., Bartos, F., Bartos, D., and Marton, L. J., Proc. Dialysis Transplant Forum. Printed by Charbray Printers, Lovettsville, VA for the Amer. Soc. for Artificial Internal Organs, Schreiner, G. E., ed., 8, 194 (1978).
Seiler, N., J. Chromatogr. 143, 221 (1977).
Veening, H., Pitt, W. W., and Jones, G., J. Chromatog. 90, 129, (1974).
Samejima, K., Kawase, M., Sakamoto, S., Okada, M., and Endo, Y., Anal. Biochem. 76, 392 (1976).
Kai, M., Ogata, T., Haraguchi, K., and Ohkura, Y., J. Chromatog. 163, 151 (1979).
Hayashi, T., Sugiura, T., Kawai, S., and Ohno, T., J. Chromatog. 145, 141 (1978).
Abdel-Monem, M. M., and Ohno, K., J. Chromatog. 107, 416 (1975).
Abdel-Monem, M. M., and Ohno, K., J. Pharm. Sci. 66, 1089 (1977).
Seiler, N., Knodgen, B., and Eisenbeiss, F., J. Chromatog. 145, 29 (1978).
Saeki, Y., Vehara, N., and Shirakawa, D., J. Chromatog. 145, 221 (1978).
Cooper, K. D., Shukla, J. B., and Rennert, O. M., Clin. Chim. Acta 82, 1 (1978).
Vandemark, F. L., Schmidt, G. J., and Slavin, W., J. Chromatog. Sci. 16, 465 (1978).
Redmond, J. W., and Tseng, A., J. Chromatog. 170, 479 (1979).
Bremer, H. J., and Kohne, E., Clin. Chim. Acta 32, 407 (1971).
Marton, L. J., Russell, D. H., and Levy, C. C., Clin. Chem. 19, 923 (1973).
Gehrke, C. W., Kuo, K. C., and Zumwalt, R. W., J. Chromatog. 89, 231 (1974).
Gehrke, C. W., Kuo, K. C., and Ellis, R. L., J. Chromatog. 143, 345 (1977).
Marton, L. J., and Lee, P. L. Y., Clin. Chem. 21, 1721 (1975).
Shipe Jr., J. R., and Savory, J., Ann. Clin. Lab. Sci. 10, 128 (1980).
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Marton, L.J. (1981). Polyamines. In: Kabra, P.M., Marton, L.J. (eds) Liquid Chromatography In Clinical Analysis. Biological Methods. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-404-3_19
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DOI: https://doi.org/10.1007/978-1-60327-404-3_19
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