Abstract
One of the main issues in statistical analysis of gene expression data is testing levels of differentially expressed genes. There are different approaches to address this issue. If in one case, given two probe sets of gene expression levels, we test whether they are differentially expressed or not, in other cases we just check whether the given sample is drawn from the prescribed distribution or not. Assuming that the prescribed distribution is normal we would like to test normality of gene expression data.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Zinger AA (1956) On a problem of A. N. Kolmogorov. Vestnik Leningradskogo Universiteta 1:53–56
Sakata T (1977) A test of normality based on some characterization theorem. Mem Fac Sci Kyushu Univ Ser A 31:221–225
Sakata T (1977) Two characterization theorems of normal density function. Mem Fac Sci Kyushu Univ Ser A 31:215–219
Bakshaev A (2010) N-distance test of uniformity on the hypersphere. Nonlinear Analysis: Modelling and Control 15:15–28
Klebanov LB (2005) N-distances and their applications. Karolinum Press, Prague
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media New York
About this protocol
Cite this protocol
Shokirov, B. (2013). Test for Normality of the Gene Expression Data. In: Yakovlev, A., Klebanov, L., Gaile, D. (eds) Statistical Methods for Microarray Data Analysis. Methods in Molecular Biology, vol 972. Humana Press, New York, NY. https://doi.org/10.1007/978-1-60327-337-4_12
Download citation
DOI: https://doi.org/10.1007/978-1-60327-337-4_12
Published:
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-60327-336-7
Online ISBN: 978-1-60327-337-4
eBook Packages: Springer Protocols