Abstract
Markov and Hidden Markov models (HMMs) are introduced using examples from linkage mapping and sequence analysis. In the course, the forward–backward, the Viterbi, the Baum-Welch (EM) algorithm, and a Metropolis sampling scheme are presented.
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Acknowledgments
CV’s work was funded in part by the FWF (SFB-F28) and AF’s work in part by the WWTF. CV wishes to thank the institute of animal breeding headed by Mathias Müller for support during the writing and especially Christian Schlötterer for encouragement and enthusiasm.
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Vogl, C., Futschik, A. (2010). Hidden Markov Models in Biology. In: Carugo, O., Eisenhaber, F. (eds) Data Mining Techniques for the Life Sciences. Methods in Molecular Biology, vol 609. Humana Press. https://doi.org/10.1007/978-1-60327-241-4_14
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DOI: https://doi.org/10.1007/978-1-60327-241-4_14
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