Abstract
Digital telemetry (DT) offers a method of collecting the electrical signals produced by neural activity and transmitting them wirelessly to a receiver/decoder for analysis and storage. The wirelessness means that activity can be recorded from a subject that is behaving relatively normally, which opens up a number of research and therapeutic opportunities – for example, in the study of spatial encoding, or in pre-seizure activity in an epileptic subject. In this chapter we first review the history of neural recording and describe the classic analog method of data processing, outlining the technical problems that need to be solved in collecting and transmitting tiny electrical signals within a noisy environment. We then outline digital signal processing together with the basic principles of telemetry, describing how DT solves these problems in a way that preserves signal fidelity while allowing subjects to move around in an unconstrained way. We finish by describing several situations in which DT is enabling advances to occur both in the laboratory and in the clinic.
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Acknowledgments
The initial DT concept was developed in collaboration with Imre Szabo and Kalman Mathe as part of an EC Framework V Project (QLG3-CT-199-00192, “N APPY”). Portions of this work were supported by NINR Grant R41 NR009877-01A1, and NINDS Grants R43 NS057839-01 and R42 NS064474-02A1 to A.A.F, and by an EC Framework 7 Project (HEALTH-F2-2007-200873, “SPACEBRAIN”) to K.J.J and J.G.D. A.A.F. and J.G.D. are founders of Bio-Signal Group Corp., a company that develops digital telemetry for commercial applications. J.G.D. and K.J.J. founded Axona Ltd., a company that sells digital electrophysiology recording systems.
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Fenton, A.A., Jeffery, K.J., Donnett, J.G. (2011). Neural Recording Using Digital Telemetry. In: Vertes, R., Stackman Jr., R. (eds) Electrophysiological Recording Techniques. Neuromethods, vol 54. Humana, Totowa, NJ. https://doi.org/10.1007/978-1-60327-202-5_4
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DOI: https://doi.org/10.1007/978-1-60327-202-5_4
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