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Peptide Bioinformatics- Peptide Classification Using Peptide Machines

  • Zheng Rong Yang
Part of the Methods in Molecular Biology™ book series (MIMB, volume 458)

Abstract

Peptides scanned from whole protein sequences are the core information for many peptide bioinformatics research subjects, such as functional site prediction, protein structure identification, and protein function recognition. In these applications, we normally need to assign a peptide to one of the given categories using a computer model. They are therefore referred to as peptide classification applications. Among various machine learning approaches, including neural networks, peptide machines have demonstrated excellent performance compared with various conventional machine learning approaches in many applications. This chapter discusses the basic concepts of peptide classification, commonly used feature extraction methods, three peptide machines, and some important issues in peptide classification.

Keywords

bioinformatics peptide classification peptide machines. 

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Copyright information

© Humana Press, a part of Springer Science + Business Media, LLC 2008

Authors and Affiliations

  • Zheng Rong Yang
    • 1
  1. 1.School of Engineering, Computer Science and MathematicsUniversity of ExeterExeter, EX4 4QFUK

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