Summary
Comparative genomic hybridization analyses have contributed greatly to our understanding of bacterial evolution, population genetics, and pathogenesis. Here, we describe a robust protocol for microarray-based comparison of genome content, which could be applied to any bacterial species of interest.
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Acknowledgments
The authors are grateful to Dan Sturdevant for providing technical information.
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© 2008 Humana Press, a part of Springer Science+Business Media, LLC
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Guinane, C.M., Fitzgerald, J.R. (2008). Microarray Comparative Genomic Hybridization for the Analysis of Bacterial Population Genetics and Evolution. In: DeLeo, F.R., Otto, M. (eds) Bacterial Pathogenesis. Methods in Molecular Biology™, vol 431. Humana Press. https://doi.org/10.1007/978-1-60327-032-8_4
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DOI: https://doi.org/10.1007/978-1-60327-032-8_4
Publisher Name: Humana Press
Print ISBN: 978-1-58829-740-2
Online ISBN: 978-1-60327-032-8
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