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Rat Models of Cardiac Insulin Resistance

  • Protocol
Vascular Biology Protocols

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 139))

Summary

Cardiovascular disease is the leading cause of death in the industrialized world. Diabetes is a major risk factor for cardiovascular disease. Unchecked diabetes can also lead to renal failure, blindness, heart attack, stroke, and amputation. The focus of this chapter will be to review the different mechanisms of insulin resistance (IR)/type 2 diabetes and various animal models used to study cardiac changes during these conditions.

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  1. Division of Pharmacology and Toxicology, The University of British Columbia, Vancouver, British Columbia, Canada

    Sanjoy Ghosh & Brian Rodrigues

  2. Center for Cardiovascular Research and Alternative Medicine, Division of Pharmaceutical Sciences, School of Pharmacy, University of Wyoming, Laramie, Wyoming, USA

    Jun Ren

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Ghosh, S., Rodrigues, B., Ren, J. (2007). Rat Models of Cardiac Insulin Resistance. In: Sreejayan, N., Ren, J. (eds) Vascular Biology Protocols. Methods in Molecular Medicine™, vol 139. Humana Press. https://doi.org/10.1007/978-1-59745-571-8_7

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