Abstract
The PRINT® (pattern replication in non-wetting templates) process has been developed as a simple, gentle way to pattern films or generate discrete particles in arrays out of either pure biological materials or biomolecules encapsulated within polymeric materials. Patterned films and particle arrays can be fabricated in a wide array of sizes and shapes using Fluorocur® (a UV-curable perfluoropolyether polymer) from the nanometer to micron scale.
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Acknowledgments
The authors would like to acknowledge outstanding scientific collaborations between the Carolina Center of Cancer Nanotech-nology Excellence, Liquidia Technologies, and the Chemistry Department at the University of North Carolina, Chapel Hill. Much of this work was carried out by a team of exceptional postdoctoral fellows and graduate students. This work was supported by NIH U54-CA-119343 (the Carolina Center of Cancer Nanotechnology Excellence), NIH F32-CA-123650 (Ruth L. Kirschstein National Research Service Award), PPG P01-GM059299-07 (Pharmacodynamics of Genes and Oligonucleotides), STC Program of the NSF (CHE-9876674), the William R. Kenan Professorship at the University of North Carolina at Chapel Hill, and through a supported research agreement with Liquidia Technologies.
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Galloway, A.L. et al. (2011). Micromolding for the Fabrication of Biological Microarrays. In: Khademhosseini, A., Suh, KY., Zourob, M. (eds) Biological Microarrays. Methods in Molecular Biology, vol 671. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59745-551-0_15
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